Production Of Transgenic Animals Notes

The three main ways of producing transgenic animals are pronuclear manipulation embryonic stem ES cell manipulation and.

Production of transgenic animals notes. Biotechnology for Sustainable Agriculture 2018. Transgenic animals have the potential of agricultural applications like improved growth rate and carcass composition improved resistance to disease increased milk. Transgenic animals can be used to produce valuable products.

Transgenic mice are developed by injecting DNA into the oocytes or 1-2 celled embryos taken from female mice. Animals that have had their DNA manipulated to possess and express a foreign gene are known as transgenic animals. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice.

Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as follows. Agricultural Applications a Breeding Farmers have always used selective breeding to produce animals that exhibit desired traits eg. To yield industrial as well as consumer product To research human diseases To produce pharmaceutical products and tissue for implantation.

The animals used for transgenic purpose naturally carry the mechanism needed to produce complex protein. The transgenic expression is not only used to breed animals which have specific traits but also to breed animals that are lacking specific genes This technique is called as knockout or gene. The first transgenic animal was produced is mice by injecting DNA to mouse embryos then implanting the embryos in female mice.

Benefits of Transgenic Animals The benefits of these animals to human welfare can be grouped into areas. Methods to produce transgenic animals. Transgenic animals are created-To study how genes are regulated and how they affect the normal functions of the body and its development.

The foreign gene is constructed using recombinant DNA methodology. Studying gene function. Genetically modified animals are proving ever more vital in.